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dc.contributor.authorOtang-Mbeng, Wilfred.en_US
dc.description.abstractEthnopharmacological relevance: The indigenous people of South Africa, such as the Khoisan, Zulu, and Ndebele, have used medicinal plants for contraception. One of the reasons for using contraception among indigenous communities is for child spacing. Aim of the study: The study aims to review medicinal plants used for contraception in South Africa as potential sources for the discovery and development of safe male and female hormonal contraceptives. Materials and methods: A literature search was conducted on medicinal plants used for contraception in South Africa by referencing textbooks and scientific databases such as Google Scholar, Science Direct, PubMed, NorthWest University Institutional Repository, National ETD Portal, government policies and documents on contraception, theses and dissertations, and other web sources such as records from SANBI and PROTA. Results: A minimum of 25 medicinal plants were identified as being used for contraception in South Africa, and these plants included local and exotic plants. Medicinal plants with contraceptive activity are Bulbine latifolia, Pouzolzia mixta, Salsola tuberculatiformis, Securidaca longipedunculata, and Typha capensis. In vivo and in vitro studies showed a decrease in mount, intromission and ejaculatory frequencies, inhibition of implantation, contraceptive effect, displaced glucocorticoids, and prolonged diestrus or had negative effects on vitality, motility, and sperm production. Conclusions: Some of the plants used for contraception in South Africa are toxic to both animals and humans. Research is needed focusing on medicinal plants used by men for contraception and by women for postcoital contraception in South Africa. Traditional healers must be included when drafting contraception policies and interventions. Medicinal plants such as B. latifolia and P. mixta demonstrated that medicinal plants used for contraception in South Africa are potential sources for the discovery and development of safe male and female hormonal contraceptives.en_US
dc.relationGrant (UID: 107748, 2016)en_US
dc.relation.ispartofJournal of ethnopharmacologyen_US
dc.subjectChild spacing.en_US
dc.subjectHormonal contraceptives.en_US
dc.subjectIndigenous medicinal plants.en_US
dc.subjectTraditional medicine.en_US
dc.titleMedicinal plants used for contraception in South Africa: a review.en_US
dc.typejournal articleen_US
dc.contributor.affiliationSchool of Biology and Environmental Sciencesen_US
dc.relation.grantnoNational Research Foundation(NRF) and North-West Universityen_US
item.openairetypejournal article-
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item.cerifentitytypePublications- of Biology and Environmental Sciences-
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